Author

Jori de Leuw

Wageningen University & Research

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Biology Disciplines

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Bioinformatics· 1

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Research Focus:benchmarking· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:protein sequence· 1

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Anne KupczokiD· 1 shared Christoforos NikolaouiD· 1 shared Emilios TassiosiD· 1 shared Nikolaos VakirlisiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBioinformatics

Anne KupczokORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintJun 6, 2025

Machine learning can identify orphans that have diverged into the ''twilight zone'' of sequence similarity

Emilios Tassios, Jori de Leuw, Christoforos Nikolaou…·Nikolaos Vakirlis

The paper uses machine learning to identify diverged orphan genes from similarity search outputs, finding that ~30% of simulated orphans are predicted to be divergent.

1 citation

humanprotein sequence

𝕏 PostBluesky