Author

Joseph R. Hamilton

University of Colorado Colorado Springs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 3 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

Guy M. HageniD· 3 shared Summer K. Levis· 3 shared Brian Lewis· 1 shared Jonathan VenturaiD· 1 shared Nasreen BuhniD· 1 shared Sriya Reddy Adunur· 1 shared Tristan C. PauliD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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3 shared papersBiophysics

Guy M. HagenORCID

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Author profile →

3 papers

Recent·Most cited

Correlative scanning electron and super-resolution structured illumination microscopy

Joseph R. Hamilton, Summer K. Levis, Guy M. Hagen

The paper compares image quality and resolution between scanning electron microscopy and super-resolution structured illumination microscopy on a mammalian testis sample.

Photonics · Aug 14, 2026Peer-reviewedBiophysics

Comparison of Deep Learning Approaches for Extreme Low-SNR Image Restoration

Nasreen Buhn, Sriya Reddy Adunur, Joseph R. Hamilton, Summer K. Levis, Guy M. Hagen, Jonathan Ventura

The paper presents a dataset for evaluating deep learning denoising methods on low-SNR fluorescence microscopy images and compares three models, finding the supervised transformer-based model performs best but requires more training time.

GigaScience · Jan 1, 2026Peer-reviewedBioinformatics

Spinning disk confocal microscopy with a 25 Megapixel Camera

Guy M. Hagen, Brian Lewis, Summer K. Levis, Joseph R. Hamilton, Tristan C. Paul

The paper presents a low-cost spinning disk confocal microscopy system using a 25 megapixel CMOS camera and custom hardware, validated with biological samples.

bioRxiv · Jul 30, 2025 · PreprintBioengineering