Engineering Transcriptional Regulator Effector Specificity using Computational Design and In Vitro Rapid Prototyping: Developing a Vanillin Sensor
Emmanuel Lorenzo Cornejo de los Santos, Joseph T Meyerowitz, Stephen L Mayo, Richard M Murray
This study designs and screens qacR variants to create a vanillin sensor using computational methods and in vitro testing, identifying two mutants that respond to vanillin in both in vitro and in vivo settings.
ACS Synthetic Biology · Aug 19, 2015Peer-reviewedSynthetic Biology