Machine Learning Predictions Surpass Individual mRNAs as a Proxy of Single-cell Protein Expression
Josephine Fisher, Oliver Wood, Samuel J. Bullers, Lynne Murray, Li Li, Matthew A Jackson
The paper compares machine learning models for predicting single-cell protein expression from RNA-seq data to mRNA levels, finding that models outperform mRNA as a proxy.
Genome biology · Apr 22, 2026Peer-reviewedBioinformatics