Mass photometry reveals stoichiometry and binding dynamics of bispecific tetravalent anti-VEGF-PD-1 antibody ivonescimab
Nina Jajcanin Jozic, Josh Bishop, Alexander Ross O'Shea, Gogulan Karunanithy, Catherine A. Lichten, Svea Cheeseman
This paper uses mass photometry to analyze the binding stoichiometry and dynamics of the bispecific antibody ivonescimab with VEGF and PD-1, finding that dimers are the most stable complex.
Antibody Therapeutics · Jul 14, 2026Peer-reviewedBiophysics