Deconvolved tumor adipocyte proportions and high grade serous ovarian carcinoma survival
Adriana Ivich, Laurie Grieshober, Natalie R. Davidson, Grace Y. Akatsu, Lauren Cole Peres, Stephanie C. Hicks, JR Marks, Joellen M. Schildkraut, Jennifer A. Doherty, Casey S. Greene
The paper deconvolves adipocyte proportions from bulk RNA-seq data of HGSOC tumors and finds higher adipocyte content is associated with worse survival.
bioRxiv · Jan 19, 2026 · PreprintGenomics