Loss of O-GlcNAcylation on MeCP2 Thr 203 Leads to Neurodevelopmental Disorders
Juanxian Cheng, Zhe Zhao, Liping Chen, Ruijing Du, Yan Wu, Qian Zhu, Ming Fan, Xiaotao Duan, Haitao Wu
This study shows that loss of O-GlcNAcylation on MeCP2 Thr 203 causes neurodevelopmental issues by impairing dendrite development and synaptic transmission.
bioRxiv · Jun 17, 2020 · PreprintNeuroscience