High-Contrast PET imaging with -NT160, a Class-IIa Histone Deacetylase (Class-IIa HDAC) Probe for In Vivo Imaging of Epigenetic Machinery in the Central Nervous System
Nashaat Turkman, Sulan Xu, Chun-Han Huang, Christopher E. Eyermann, Julia Salino, Palwasha Khan
This paper develops [18F]-NT160, a PET tracer for imaging class-IIa HDACs in the brain, showing high-contrast imaging and specific uptake patterns across brain regions.
bioRxiv · Nov 12, 2022 · PreprintNeuroscience