Telmisartan and Lisinopril Show Potential Benefits in Rescuing Cognitive-Behavioral Function Despite Limited Improvements in Neuropathological Outcomes in Tg-SwDI Mice
Natalia Motzko Noto, Yazmin M. Restrepo, Ariana Hernandez, Chana Vogel, Victoria Pulido-Correa, Shay Moen, Julianna Bonetti, Vedika Chiduruppa, Robert Charles Speth, Lisa S. Robison
This study evaluates the effects of telmisartan and lisinopril on cognitive-behavioral function and neuropathology in Tg-SwDI mice, finding some cognitive rescue without significant Aβ reduction.
bioRxiv · Apr 23, 2025 · PreprintNeuroscience