Essentially leading antibody production: An investigation of amino acids, myeloma and natural V-region signal peptides in producing Pertuzumab and Trastuzumab variants
Wei‐Li Ling, Chinh Tran-To Su, Wai‐Heng Lua, Jun-Jie Poh, Yuen-Ling Ng, Anil Wipat, Samuel Ken‐En Gan
The paper investigates how varying signal peptides and amino acid counts affect recombinant antibody production rates in HEK293 cells, developing a predictive model for transient production.
Frontiers in Immunology · Dec 7, 2020Peer-reviewedMolecular Biology