Samuel Ken‐En Gan

This study investigates how Ara h 2 and FcϵRI binding affect IgE structural dynamics and allosteric communication, revealing conformational changes and shifts in communication pathways.

The paper improves the signal peptide of the Ag43 autotransporter in E. coli to enhance surface display of sfGFP using epPCR and single-cell sorting.

The paper optimizes transfection and culture parameters in HEK293E cells to enhance recombinant antibody production, achieving a 4-fold increase in light chain production and a 2.5-fold increase in whole antibody production.

The paper investigates how varying signal peptides and amino acid counts affect recombinant antibody production rates in HEK293 cells, developing a predictive model for transient production.

The paper calculates the probabilities of amino acid changes from single nucleotide substitutions in the genetic code and reveals a self-preserving organization that reduces disruptive physicochemical changes.