Molecular basis of inhibition of the amino acid transporter B0AT1 (SLC6A19)
Junyang Xu, Ziwei Hu, Lu Dai, Aditya Yadav, Yashan Jiang, Angelika Bröer, Michael G. Gardiner, Malcolm Donald McLeod, Renhong Yan, Stefan Bröer
This paper identifies high-affinity inhibitors of B0AT1 and elucidates their mechanism of action through cryo-EM structures.
Nature Communications · Aug 22, 2024Peer-reviewedBiochemistry