Somatic mutation phasing and haplotype extension using linked-reads in multiple myeloma
Steven M. Foltz, Yize Li, Lijun Yao, Nadezhda V. Terekhanova, Amila Weerasinghe, Qingsong Gao, Guanlan Dong, Moses Schindler, Song Cao, Hua Sun, Reyka G. Jayasinghe, Robert S. Fulton, Catrina C. Fronick, Justin A. King, Daniel R. Kohnen, , Li Ding
This study uses linked-read sequencing to phase somatic mutations in multiple myeloma, extending haplotype blocks and revealing phasing patterns in key mutated genes.
bioRxiv · Aug 9, 2024 · PreprintBioinformatics