Dual RNAseq shows the human mucosal immunity protein, MUC13, is a hallmark of Plasmodium exoerythrocytic infection
Gregory M. LaMonte, Pamela Orjuela-Sanchez, Lawrence Wang, Shangzhong Li, Justine Swann, Annie N. Cowell, Bing Yu Zou, Alyaa M. Abdel-Haleem Mohamed, Zaira Villa-Galarce, Marta Moreno, Carlos Tong-Rios, Joseph M. Vinetz, Nathan Lewis, Elizabeth A. Winzeler
The paper identifies MUC13 as upregulated in Plasmodium exoerythrocytic hepatic-stage infection and shows it can be used to identify anti-parasite compounds.
bioRxiv · Oct 2, 2017 · PreprintMicrobiology