Author

Jyothish Thomas

Science and Technology Facilities Council

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Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

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Agnel Praveen JosephiD· 1 shared Jeyan ThiyagalingamiD· 1 shared Luc G. ElliottiD· 1 shared Nicholas WhyattiD· 1 shared Niraj BhujeliD· 1 shared Sony MalhotraiD· 1 shared Tamilarasan Sabapathy· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Agnel Praveen JosephORCID

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1 paper

Recent·Most cited

DPI-score: A deep learning-based metric for assessing protein-protein interfaces in cryo-EM derived assemblies

Niraj Bhujel, Nicholas Whyatt, Agnel Praveen Joseph, Jyothish Thomas, Luc G. Elliott, Tamilarasan Sabapathy, Jeyan Thiyagalingam, Sony Malhotra

The paper introduces DPI-Score, a deep learning metric to assess protein-protein interfaces in cryo-EM structures, showing it can detect interface errors not found by density-based scores.

bioRxiv · Jul 21, 2026 · PreprintBioinformatics