Preferential binding of human BRCA1 protein with open X-like conformation of Holliday junction, a homologous recombination intermediate
Sahil Hasan Kabir, K Vishnupriya, Nibedita Pal
This study shows BRCA1 preferentially binds the open X-like conformation of Holliday junctions and interacts with charged/polar amino acids, many of which are sites of missense mutations.
International Journal of Biological Macromolecules · May 8, 2025Peer-reviewedBiophysics