Pan-species transcriptomic analysis reveals a constitutive adaptation against oxidative stress for the highly virulent Leptospira species.
A. Giraud Gatineau, G. Ayachit, C. Nieves, C. Dagbo, K. Bourhy, F. Pulido, S. Huete, N. Benaroudj, M. Picardeau, F. J. Veyrier
The paper introduces Annotator-RNAtor for pan-species transcriptomic analysis and applies it to study adaptation in Leptospira species, finding higher katE expression in virulent P1+ strains linked to oxidative stress tolerance.
bioRxiv · Aug 1, 2023 · PreprintMicrobiology