Author

K. C. Rouen

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

C. E. Clancy· 1 shared D. L. Mateos· 1 shared H. Wulff· 1 shared I. Vorobyov· 1 shared K. Ngo· 1 shared S.-H. Ahn· 1 shared V. Yarov-Yarovoy· 1 shared Y. Han· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

C. E. Clancy

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1 paper

Recent·Most cited

Elucidating Molecular Mechanisms of Protoxin-2 State-specific Binding to the Human NaV1.7 Channel

K. Ngo, D. L. Mateos, Y. Han, K. C. Rouen, S.-H. Ahn, H. Wulff, C. E. Clancy, V. Yarov-Yarovoy, I. Vorobyov

This study uses computational modeling to investigate how protoxin-2 binds to different states of the hNaV1.7 channel, identifying key residues and lipid interactions that contribute to its selectivity.

bioRxiv · Feb 27, 2023Biophysics