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K. I. Woroniecka

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Approach:statistical model· 1

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H. Yan· 1 shared L. Chen· 1 shared L. Hansen· 1 shared R. Yang· 1 shared Y. He· 1 shared

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1 shared paperCancer Biology

H. Yan

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1 paper

Recent·Most cited

Cancer BiologybioRxivMay 24, 2018

MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization

L. Hansen, R. Yang, K. I. Woroniecka…·Y. He

The paper shows MTAP loss in GBM correlates with an immunosuppressive profile by increasing M2 macrophages and that MTA, a byproduct of MTAP loss, promotes this effect through the A2B receptor.

DOI 10.1038/s41598-022-07697-0

humanbulk RNA-seq

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