Massively parallel single-cell sequencing of genetic loci in diverse microbial populations
F. Lan, J. Saba, T. D. Ross, Z. Zhou, K. Krauska, K. Anantharaman, R. Landick, O. S. Venturelli
This paper introduces DoTA-seq, a method for single-cell sequencing of genetic loci in microbial populations, and demonstrates its application in studying phase-variable operons and antibiotic resistance gene shifts.
bioRxiv · Nov 21, 2022 · PreprintMicrobiology