Author

K. L. O'Shea

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. E. Murmann· 1 shared B. Paudel· 1 shared E. T. Bartom· 1 shared M. E. Peter· 1 shared M. Kocherginsky· 1 shared M. Patel· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

A. E. Murmann

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1 paper

Recent·Most cited

Identification of the toxic 6mer seed consensus in human cancer cells

M. Patel, E. T. Bartom, B. Paudel, M. Kocherginsky, K. L. O'Shea, A. E. Murmann, M. E. Peter

The paper identifies GGGGGC as the most toxic 6mer seed in human cancer cells, confirming its mechanism through targeted gene disruption and reporter assays.

bioRxiv · Dec 22, 2020Cancer Biology