High-Throughput Developability Assays Enable Library-Scale Identification of Producible Protein Scaffold Variants
A. W. Golinski, K. M. Mischler, S. Laxminarayan, N. Neurock, M. Fossing, H. Pichman, S. Martiniani, B. J. Hackel
This study develops high-throughput assays to predict protein developability, enabling large-scale identification of producible variants with improved expression, solubility, and stability.
bioRxiv · Dec 14, 2020Bioengineering