Author

K. Mamis

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Biology Disciplines

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Cancer Biology· 2

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

I. Bozic· 2 shared R. Zhang· 1 shared

Activity by Year

2023-2024 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersCancer Biology

I. Bozic

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2 papers

Recent·Most cited

Early-stage cancer results in a multiplicative increase in cell-free DNA originating from healthy tissue

K. Mamis, I. Bozic

The paper quantifies how early-stage cancer increases cell-free DNA levels from healthy tissue, not tumors, and explains this through a saturation model of clearance.

bioRxiv · Jan 26, 2024Cancer Biology

Stochastic model for cell population dynamics quantifies homeostasis in colonic crypts and its disruption in early tumorigenesis

K. Mamis, R. Zhang, I. Bozic

The paper develops a stochastic model of colonic crypt cell dynamics to quantify homeostasis and predict early tumorigenesis by analyzing the effects of APC and KRAS mutations.

bioRxiv · Mar 19, 2023Cancer Biology