Disseminating cells in human tumours acquire an EMT cancer stem cell state that is predictive of metastasis
G. Youssef, L. Gammon, L. Ambler, S. Lunetto, A. Scemama, H. Cottom, K. Piper, I. C. Mackenzie, M. P. Philpott, A. Biddle
The paper identifies disseminating EMT cancer stem cells in human oral cancer specimens using EpCAM, CD24, and Vimentin markers, which predict metastasis with high accuracy.
bioRxiv · Apr 7, 2020Cancer Biology