Author

M. P. Philpott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

C. L. Bishop· 3 shared L. Gammon· 3 shared A. Biddle· 2 shared G. Youssef· 2 shared I. C. Mackenzie· 2 shared J. C. Garbe· 2 shared J. Koh· 2 shared M. R. Stampfer· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

C. L. Bishop

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

SenPred: A single-cell RNA sequencing-based machine learning pipeline to classify senescent cells for the detection of an in vivo senescent cell burden

B. Hughes, A. Davis, D. Milligan, R. Wallis, M. P. Philpott, L. J. Wainwright, D. A. Gunn, C. L. Bishop

SenPred uses scRNA-seq to classify senescent cells and detects in vivo senescent cell burden with high accuracy.

bioRxiv · Oct 23, 2023 · PreprintCell Biology

A CD24+CD271+ Melanoma Cancer Stem Cell Possesses Hybrid Characteristics of its Single Marker Counterparts and Promotes Invasion and Therapeutic Resistance

O. Knowles, P. Doldan, I. Hillier-Richardson, S. Lunt, G. Youssef, L. Gammon, I. C. Mackenzie, M. P. Philpott, H. Rizvi, D. Bergamaschi, C. A. Harwood, A. Biddle

The paper identifies a CD24+CD271+ melanoma sub-population with hybrid characteristics and enhanced invasive and therapeutic resistance properties.

bioRxiv · Jun 7, 2023Cancer Biology

Early growth response 2 (EGR2) is a novel regulator of the senescence program

E. J. Tyler, A. Gutierrez Del Arroyo, R. Wallis, B. K. Hughes, J. C. Garbe, M. R. Stampfer, J. Koh, R. Lowe, M. P. Philpott, C. L. Bishop

This study identifies EGR2 as a novel regulator of senescence by activating the ARF and p16 promoters and reversing the senescent phenotype upon its ablation.

bioRxiv · Sep 30, 2020Cell Biology

Disseminating cells in human tumours acquire an EMT cancer stem cell state that is predictive of metastasis

G. Youssef, L. Gammon, L. Ambler, S. Lunetto, A. Scemama, H. Cottom, K. Piper, I. C. Mackenzie, M. P. Philpott, A. Biddle

The paper identifies disseminating EMT cancer stem cells in human oral cancer specimens using EpCAM, CD24, and Vimentin markers, which predict metastasis with high accuracy.

bioRxiv · Apr 7, 2020Cancer Biology

Ribosomal stress-induced senescence as a novel pro-senescence strategy for p16 positive basal-like breast cancer

M. Moore, L. Gammon, S. Dreger, J. Koh, J. C. Garbe, M. R. Stampfer, M. P. Philpott, L. J. Jones, C. L. Bishop

This study identifies ribosomal proteins as pro-senescence targets in p16 positive basal-like breast cancer, showing their role in inducing stable cell cycle arrest and poor prognosis.

bioRxiv · Nov 14, 2018 · PreprintCancer Biology