Oxaliplatin-induced cardiotoxicity in mice is connected to the changes in energy metabolism in the heart tissue
J. Du, L. C. Sudlow, K. Shahverdi, H. Zhou, M. Michie, T. H. Schindler, J. D. Mitchell, S. Mollah, M. Y. Berezin
This study shows that chronic oxaliplatin treatment in mice causes metabolic shifts in heart tissue, leading to cardiotoxicity and potential diagnostic and therapeutic targets.
bioRxiv · May 24, 2023Pharmacology & Toxicology