Author

K. Spiru

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

H. Wan· 1 shared R. A. Pearlstein· 1 shared S. Williams· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperPharmacology & Toxicology

H. Wan

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1 paper

Recent·Most cited

General structure-free energy relationships of hERG blocker binding under native cellular conditions

H. Wan, K. Spiru, S. Williams, R. A. Pearlstein

The paper analyzes hERG blocker binding using solvation field principles, showing correlations between solvation costs and blocker potency and safety.

bioRxiv · Oct 7, 2021 · PreprintPharmacology & Toxicology