Mechanical Stimuli such as Shear Stress and Piezo1 Stimulation Generate Red Blood Cell Extracellular Vesicles
G. S. Sangha, C. M. Weber, R. M. Sapp, S. Setua, K. Thangaraju, M. Pettebone, A. Doctor, P. W. Buehler, A. M. Clyne
This study develops an in vitro model to generate RBC-EVs under shear stress and optimizes isolation methods to improve yield and purity for vascular research.
bioRxiv · Oct 4, 2022 · PreprintBioengineering