Selectivity and evolution of Aqp10 in solute permeability influenced by pore molecular weight
A. Nagashima, K. Ushio, H. Nishihara, J. Akimoto, A. Kato, T. Furuta
This study identifies the molecular mechanism behind the reduced solute permeability in Aqp10.2 by analyzing ancestral sequences, structural models, and site-directed mutagenesis.
bioRxiv · Mar 16, 2024Physiology