Chronic Intermittent Hypobaric Hypoxia Prevents Contrast-Induced Acute Kidney Injury By Modulating The HIF-1α Signaling Pathway
L. Zhang, Y.-h. Ni, G.-y. Cao, J.-y. Zhang, B.-j. Yi, Z.-h. Pang, H.-j. Ma, K.-m. Yin
This study shows that chronic intermittent hypobaric hypoxia prevents contrast-induced acute kidney injury in rats by activating the HIF-1/BNIP3 pathway to enhance antioxidant capacity and mitochondrial autophagy.
bioRxiv · Feb 7, 2022 · PreprintPhysiology