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Ka Hin Toby Mak

The University of Sydney

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Biochemistry· 1

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Approach:experimental assay· 1

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Anthony CerraiD· 1 shared Bernhard C. LechtenbergiD· 1 shared David KomanderiD· 1 shared Ethan D. Goddard‐BorgeriD· 1 shared Jenny JiouiD· 1 shared John SilkeiD· 1 shared Leo CorciliusiD· 1 shared Marco JochemiD· 1 shared

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Anthony CerraORCID

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1 paper

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BiochemistryLife Science AlliancePeer-reviewedApr 1, 2025

The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-proteinaceous substrates in vitro

Xiangyi S. Wang, Jenny Jiou, Anthony Cerra…·Bernhard C. Lechtenberg

This study demonstrates that HOIL-1 can ubiquitinate non-proteinaceous substrates like saccharides in vitro, identifies a key residue for this activity, and produces ubiquitinated saccharides as potential tools.

11 citations

experimental assay

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