Spatiotemporal profiling of T cell repertoires in Lynch syndrome reveals convergent immune responses through neoplastic progression
Penelope Edwards, Ottilie Swinyard, Tahel Ronel, Yanrong Jiang, Gayathri Nageswaran, Chirine Sakr, Suhana Yasmin, Heather Grant, Smith Eleanor, Konstantin Braeutigam, Sindhu Varughese, Pooja Datt, Adriana Martinez, Jennifer Fisher, Benny Chain, , Trevor A Graham
This study profiles T cell repertoires in Lynch syndrome patients to show convergent immune responses during neoplastic progression.
bioRxiv · Oct 12, 2026 · PreprintImmunology