Author

Chirine Sakr

Institute of Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Adrian LärkerydiD· 1 shared Adriana Martinez· 1 shared Alan A. MelcheriD· 1 shared Amy BurleyiD· 1 shared Ananya ChoudhuryiD· 1 shared Ann-Marie Baker· 1 shared Anna Clare WilkinsiD· 1 shared Barry A. Gusterson· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Adrian LärkerydORCID

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2 papers

Recent·Most cited

Spatiotemporal profiling of T cell repertoires in Lynch syndrome reveals convergent immune responses through neoplastic progression

Penelope Edwards, Ottilie Swinyard, Tahel Ronel, Yanrong Jiang, Gayathri Nageswaran, Chirine Sakr, Suhana Yasmin, Heather Grant, Smith Eleanor, Konstantin Braeutigam, Sindhu Varughese, Pooja Datt, Adriana Martinez, Jennifer Fisher, Benny Chain, , Trevor A Graham

This study profiles T cell repertoires in Lynch syndrome patients to show convergent immune responses during neoplastic progression.

bioRxiv · Oct 12, 2026 · PreprintImmunology

Spatially-resolved multimodal profiling identifies functionally-heterogeneous cancer-associated fibroblasts associated with poor radiotherapy outcomes in muscle-invasive bladder cancer.

Amy Burley, Katie O’Fee, Morgane Dromby, Mi Chween Chan, Barry A. Gusterson, Adrian Lärkeryd, Emma Westlund, Priya Narayanan, Chirine Sakr, Tatiany Silveira, Rose Foster, Mikel Portillo, Marc Rabionet Diaz, Tom Lund, Alan A. Melcher, , Anna Clare Wilkins

This study identifies functionally heterogeneous cancer-associated fibroblasts in muscle-invasive bladder cancer linked to poor radiotherapy outcomes.

bioRxiv · Sep 22, 2026 · PreprintCancer Biology