From Cardiac Myosin to the Beta Receptor: Autoantibodies Promote a Fibrotic Transcriptome and Reduced Ventricular Recovery in Human Myocarditis
Jennifer M. Myers, Clayton Sandel, Kathy M Alvarez, Lori Garman, Graham B. Wiley, Courtney G. Montgomery, Patrick M. Gaffney, Stavros Stavrakis, DeLisa Fairweather, Katelyn A. Bruno, Yan Daniel Zhao, Leslie T. Cooper, Madeleine White Cunningham
This study identifies cardiac myosin autoantibodies associated with reduced ejection fraction and fibrotic transcriptomes in nonrecovered myocarditis patients.
bioRxiv · Jun 19, 2024 · PreprintImmunology