Tissue transcriptomics of endomyocardial biopsies reveals widespread molecular perturbations independent of leukocyte-rich foci in human myocarditis
Charles D. Cohen, Jiali H. He, Kevin Christian Bermea, Sylvie T. Rousseau, Adam Luo, Obialunanma V. Ebenebe, Kelly Casella, Emanuele Palescandolo, Kory J. Lavine, Eugene Shenderov, Marc K. Halushka, Luigi Adamo
This study uses spatial transcriptomics to show that myocarditis involves widespread molecular changes in cardiomyocytes, not just immune cell areas.
Journal of Molecular and Cellular Cardiology Plus · Mar 1, 2026Peer-reviewedImmunology