Differential expression of a disease-associated MRE11 variant reveals distinct phenotypic outcomes
McKenna B. DeFoer, Ahmed M Mostafa, Andrea J. Hartlerode, S Orbán, Ken McDonough, Sophie Quirk, Brianna K L Ferguson, David O. Ferguson, JoAnn Sekiguchi
This study investigates the phenotypic outcomes of reduced MRE11-ATLD1 expression in mice, revealing anemia, bone marrow failure, and impaired lymphocyte development.
Human Molecular Genetics · Sep 23, 2025Peer-reviewedGenetics