Nucleolar translocation of human DNA topoisomerase II by ATP depletionand its disruption by the RNA polymerase I inhibitor BMH-21
Keiko Morotomi‐Yano, Ken-ichi Yano
This study shows that ATP depletion causes Top2A and Top2B to translocate to the nucleolus, and BMH-21 disrupts this nucleolar retention.
Scientific Reports · Nov 2, 2021Peer-reviewedMolecular Biology