Author

Kerry A. Flegel

University of Michigan

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Developmental Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Ajai J. Pulianmackal· 1 shared Ella Gourley· 1 shared Emily Rozich· 1 shared Kiriaki Kanakousaki· 1 shared Laura ButtittaiD· 1 shared Olga G. GrushkoiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperDevelopmental Biology

Ajai J. Pulianmackal

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1 paper

Recent·Most cited

Mis-regulation of the Nucleoporins 98 and 96 lead to defects in protein synthesis that promote hallmarks of tumorigenesis.

Ajai J. Pulianmackal, Kiriaki Kanakousaki, Kerry A. Flegel, Olga G. Grushko, Ella Gourley, Emily Rozich, Laura Buttitta

This study shows that reducing Nup98-96 function in Drosophila leads to defects in protein synthesis and JNK signaling, promoting tumorigenesis when apoptosis is inhibited.

Disease Models & Mechanisms · Feb 2, 2022Peer-reviewedDevelopmental Biology