Utilizing combined spatial transcriptomics to elucidate localized immune responses within human coronary arteries throughout the progression of atherosclerosis
Joana Campos, Jack L. McMurray, Michelangelo Certo, Ketaki Hardikar, Chris Morse, C. Russell Corfield, Melanie Weigand, Desley Neil, Pasquale Maffia, Claudio Mauro
This study uses spatial transcriptomics to analyze immune cell organization in human coronary arteries across atherosclerosis stages, identifying relevant pathways and molecules for therapeutic targets.
bioRxiv · Feb 20, 2025 · PreprintImmunology