Development of an image-guided non-vitrectomy subretinal access approach for trans-scleral cell and gene therapy delivery
Mandeep S. Singh, Shoujing Guo, Christopher B. Toomey, Minda M. McNally, Sarah Harris‐Bookman, Kang V. Li, Dzhalal Agakishiev, Shuwen Wei, Soohyun Lee, Kathleen M. Perrino, Kevin C. Wolfe, Jin Ung Kang
The paper develops an image-guided minimally invasive subretinal access approach for cell and gene therapy delivery, demonstrating feasibility in animal models but encountering technical challenges.
bioRxiv · Feb 25, 2025 · PreprintBioengineering