D3 nutraceutical pre-supplementation ameliorates behavioral, ionotropic receptors, and synaptic proteins alterations in a MK-801 induced mouse model of schizophrenia
Omalur Eshwari, Kishore Golla, Shashikant Patel, Vijay Yenagi, Roli Kushwaha, Sharon Mariam Abraham, Sumana Chakravarty, Raghavendra Bheemappa Nayak, Pragya Komal
This study shows that vitamin D3 supplementation before MK-801-induced schizophrenia-like symptoms in mice improves behavioral deficits and restores gene expression of NMDA receptor subunits and nicotinic acetylcholine receptors.
bioRxiv · Jun 26, 2026 · PreprintNeuroscience