Determining the genetic basis of anthracycline-cardiotoxicity by molecular response QTL mapping in induced cardiomyocytes
David A. Knowles, Courtney K. Burrows, John Blischak, Kristen M Patterson, Daniel Serie, Nadine Norton, Carole Ober, Jonathan K. Pritchard, Yoav Gilad
This study identifies genetic variants influencing the transcriptomic response to doxorubicin in cardiomyocytes and links them to anthracycline-induced cardiotoxicity risk.
eLife · May 7, 2018Peer-reviewedGenomics