The Epigenetic Pacemaker is a more sensitive tool than penalized regression for identifying moderators of epigenetic aging
Colin P. Farrell, Kalsuda Lapborisuth, Chanyue Hu, Kyle Pu, Sagi Snir, Matteo A. Pellegrini
The paper compares the epigenetic pacemaker (EPM) to traditional epigenetic clocks, finding EPM more sensitive in detecting factors affecting epigenetic age.
bioRxiv · Oct 5, 2021 · PreprintGenetics