Author

Kalsuda Lapborisuth

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Colin P. FarrelliD· 3 shared Matteo A. PellegriniiD· 3 shared Sagi SniriD· 2 shared Chanyue HuiD· 1 shared Keshiv Tandon· 1 shared Kyle Pu· 1 shared Rahil Modi· 1 shared Roberto FerrariiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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3 shared papersGenetics

Colin P. FarrellORCID

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3 papers

Recent·Most cited

The Multi-State Epigenetic Pacemaker enables the identification of combinations of factors that influence DNA methylation

Colin P. Farrell, Keshiv Tandon, Roberto Ferrari, Kalsuda Lapborisuth, Rahil Modi, Sagi Snir, Matteo A. Pellegrini

The paper introduces MSEPM, a multidimensional model for DNA methylation that accounts for age, sex, and cell type, revealing site-specific methylation dynamics influenced by transcription factors.

GeroScience · Nov 16, 2024Peer-reviewedBioinformatics

Pseudotime analysis reveals exponential trends in DNA methylation aging with mortality associated timescales

Kalsuda Lapborisuth, Colin P. Farrell, Matteo A. Pellegrini

This study uses pseudotime analysis to show DNA methylation aging follows exponential trends linked to mortality timescales.

Cells · Feb 22, 2022Peer-reviewedGenetics

The Epigenetic Pacemaker is a more sensitive tool than penalized regression for identifying moderators of epigenetic aging

Colin P. Farrell, Kalsuda Lapborisuth, Chanyue Hu, Kyle Pu, Sagi Snir, Matteo A. Pellegrini

The paper compares the epigenetic pacemaker (EPM) to traditional epigenetic clocks, finding EPM more sensitive in detecting factors affecting epigenetic age.

bioRxiv · Oct 5, 2021 · PreprintGenetics