BiochemistrybioRxiv
Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids
A. E. Aleshin, Y. Yao, A. Iftikar…·F. M. Marassi
This study determines the atomic structure of PLEKHA7's PH domain and reveals its multivalent interaction mechanism with membrane-bound PIPs, providing insights for inhibitor design.
DOI 10.1016/j.str.2021.03.018