The initiation knot is a signaling center required for molar tooth development
I. Mogollon, J. E. Moustakas-Verho, M. Niittykoski, L. Ahtiainen
The paper identifies the molar initiation knot as a transient signaling center essential for tooth development, showing it drives the formation of the primary enamel knot through Wnt and Shh interactions.
bioRxiv · Apr 9, 2020Cell Biology