Optimally designed vs intuition-driven inputs: the study case of promoter activity modelling
L. Bandiera, V. Kothamachu, E. Balsa-Canto, P. S. Swain, F. Menolascina
The paper compares parameter estimation in a yeast promoter model using typical and optimally designed experiments, finding a 70% improvement in predictive ability with optimal design.
bioRxiv · Jun 14, 2018 · PreprintBioengineering