Author

L. Bossi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

P. Bouloc· 3 shared J. Casadesus· 2 shared N. Figueroa-Bossi· 2 shared P. Kerboriou· 2 shared A. Blanc-Potard· 1 shared A.-A. Gonzalez· 1 shared B. Felden· 1 shared C. Begon-Pescia· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

P. Bouloc

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transcription-driven DNA supercoiling activates bacterial chromatin at a distance

N. Figueroa-Bossi, R. Fernandez-Fernandez, P. Kerboriou, P. Bouloc, J. Casadesus, M.-A. Sanchez-Romero, L. Bossi

The paper shows transcription-induced counter-silencing of H-NS-repressed genes occurs at a distance through DNA supercoiling diffusion.

bioRxiv · Oct 26, 2023 · PreprintMicrobiology

Dynamics of macrophage polarization support Salmonella persistence in a whole living organism

J. Leiba, T. Sipka, C. Begon-Pescia, M. Bernardello, S. Tairi, L. Bossi, A.-A. Gonzalez, X. Mialhe, E. Gualda, P. Loza-Alvarez, A. Blanc-Potard, G. Lutfalla, M. Nguyen-Chi

This study uses a zebrafish model to show Salmonella persists in non-inflammatory macrophage clusters by altering macrophage polarization and adhesion programs during infection.

bioRxiv · May 9, 2023Immunology

Pervasive transcription enhances the accessibility of H-NS-silenced promoters and generates bistability in Salmonella virulence gene expression

N. Figueroa, M. A. Sanchez-Romero, P. Kerboriou, D. Naquin, C. Mendes, P. Bouloc, J. Casadesus, L. Bossi

The paper shows that inhibiting Rho-dependent transcription termination in Salmonella allows spurious antisense transcription to displace H-NS, enabling SPI-1 gene expression and generating bistability.

bioRxiv · Apr 26, 2022Microbiology

6S RNA-dependent antibiotic susceptibility

M. Esberard, M. Hallier, W. Liu, C. Morvan, L. Bossi, N. Figueroa-Bossi, B. Felden, P. Bouloc

This study identifies 6S RNA's role in enhancing rifampicin resistance in Staphylococcus aureus and shows similar effects in other pathogens.

bioRxiv · Jan 31, 2022Microbiology