Author

L. Boukas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

H. T. Bjornsson· 2 shared A. Barski· 1 shared A. Razi· 1 shared A. W. Lindsley· 1 shared B. N. Simpson· 1 shared C. Schafer· 1 shared D. Qu'd· 1 shared K. D. Hansen· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

H. T. Bjornsson

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Author profile →

2 papers

Recent·Most cited

KMT2D regulates thymic egress by modulating maturation and integrin expression

S. J. Potter, L. Zhang, M. Kotliar, Y. Wu, C. Schafer, K. Stefan, L. Boukas, D. Qu'd, O. Bodamer, B. N. Simpson, A. Barski, A. W. Lindsley, H. T. Bjornsson

This study shows that KMT2D regulates thymic egress by affecting maturation and integrin expression in T cells, leading to immune dysfunction in Kabuki syndrome type 1.

bioRxiv · Oct 4, 2022 · PreprintImmunology

Natural selection acts on epigenetic marks

L. Boukas, A. Razi, H. T. Bjornsson, K. D. Hansen

The paper develops a test for natural selection on epigenetic marks and finds that promoter DNA methylation, H3K4me3, and H3K36me3 are under selection, likely due to their role in gene regulation and mutation rate modification.

bioRxiv · Jul 4, 2020 · PreprintEvolutionary Biology