Author

L. Casas-Fraile

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

A. De Roover· 1 shared A. Escribano· 1 shared A. Sermon· 1 shared C. Cherifi· 1 shared F. Cailotto· 1 shared F. Cornelis· 1 shared R. Lories· 1 shared S. Monteagudo· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

A. De Roover

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1 paper

Recent·Most cited

Cell BiologybioRxivMay 14, 2021

Hypoxia induces transcription of DOT1L in articular cartilage to protect against osteoarthritis

A. De Roover, A. Escribano, F. Cornelis…·S. Monteagudo

This study identifies hypoxia-induced DOT1L transcription as a protective mechanism against osteoarthritis and shows that hypoxia mimetics can restore DOT1L function and slow disease progression.

DOI 10.1172/jci.insight.150451

mousebulk RNA-seq

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